All functions

Check_CountTable_Format()

Check the Input Count Table Format

cal_p()

Calculate the significance of the dynamic signal for a single gene's single time expression. Compared to baseline NB confidence interval.

cal_time_p_single_gene()

Calculate the significance of the dynamic signal for a single gene's over alll the time points.

combine_p_single_gene()

Combine multiple p-value using Fisher's p-value combination method.

curveFitting.new()

CurveFitting function

draw_CurveComp()

Draw DDEGs from one biological pathway from two master.list objects and also show LOESS curve fitting for both experimental groups

draw_CurveComp_Perm()

Draw DDEGs from one biological pathway from two master.list objects and also show LOESS curve fitting for both experimental groups, and perform permutation test

draw_GOHeatmap()

Draw GOHeatmap containing Terms from TimeHeatmap and included Genes

draw_GeneTraj()

Draw gene(s) trajectory with observed data and fitted data

draw_TimeHeatmap_GO()

Draw TimeHeatmap Using Gene Ontology (GO) Enrichment

draw_TimeHeatmap_enrichR()

Draw TimeHeatmap Using enrichR

draw_TimeHeatmap_selGO()

Subset TimeHeatmap by providing a manually selected non-redundant GO terms

draw_TrajClusterGrid()

Draw Grouped DDEGs Trajectories in Grid Plot

draw_TrajClusterPie()

Draw Grouped DDEGs Main-type and Sub-type Composition in Hierarchical Pie Chart

fit_single_gene_const()

Fit the baseline count data into a constant negative binomial model.

fit_single_gene_spline()

Fit the non-baseline count data into a smoothed ANOVA model.

get_GeneEnsembl2Symbol()

ID convention (from ENSEMBL to SYMBOL)

get_Symbol2GeneEnsembl()

ID convention (from SYMBOL to ENSEMBL)

get_rep_array()

Get the replicate array from count table

get_time_array()

Get the time array from count table

permutation.new()

Permutation test

preprocess_TrendCatcher()

Preprocessing for TrendCatcher

run_TrendCatcher()

Run TrendCatcher Main Algorithm

transform_single_gene_df()

Convert a single gene's count row number into data frame with two columns.